the real facts about Viagra

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Viagra is a brand name for a drug used to treat erectile dysfunction (impotence): the inability to get and maintain an erection. It is also used in the treatment of specific high blood pressure of the heart and the arteries that supply the lungs. The generic name of the medicine is sildenafil (pronounced sill-den-a-fill).


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Like many great scientific discoveries, the benefits of Viagra for treating erectile dysfunction were discovered by accident. Pharmaceutical company Pfizer initially developed the drug in 1989 as a treatment for high blood pressure and angina pectoris.

Unfortunately early clinical trials were not positive. In order to have the good effect, the drug had to be taken three times a day and it caused muscle pain in some patients. It was also found to interact with nitrates (the standard treatment for angina pectoris), which resulted in a dangerous drop in patients’ blood pressure.

Fortunately, some patients have reported the delayed side effect of erections. As a result, the focus on Viagra has shifted to its sexual applications.

After clinical testing, it was approved for use in Australia in 1998, after being approved in the United States nine months earlier.

How it works

Viagra works by binding to an enzyme called phosphodiesterase. Viagra’s binding to the enzyme prevents it from converting the chemical cyclic guanosine monophosphate (abbreviated cGMP) to guanosine triphosphate (GTP).

The effect of an accumulation of cGMP is the relaxation of the artery walls. This enlarges the arteries and thus allows more blood to flow through the penis.

However, the drug will not give patients an erection without sexual stimulation. When a man is aroused, the brain sends a signal to cells in the penis to release nitric oxide, which activates the production of cGMP. Without the stimulation to produce nitric oxide, there is no accumulation of cGMP and no erection.

Administration

All forms of the drug are sold as solid oral tablets in doses between 25 and 100 milligrams. For the treatment of high blood pressure, tablets are also available in doses of 20 milligrams.

The dose prescribed by the doctor takes into account the patient’s age, the underlying cause of his impotence and his kidney function.

When used to treat erectile dysfunction, patients should take the drug once a day, 30 minutes to an hour before their planned sexual activity. The effects of the medicine will take longer to appear if it is taken with food.

Side effects

One in ten patients will feel common side effects of Viagra. Side effects include the development of a rash, diarrhea, and increased susceptibility to urinary tract infections.

A less common side effect is abnormal vision. This includes blurred vision, sensitivity to light and / or a blue-green tint of the patient’s vision called cyanopsy. Higher doses increase the risk that a patient will have abnormal vision.

Unusual alternative uses

The flowers stay more upright when dosed with Viagra.
Velodenz / Flickr, CC BY

Besides its approved medical uses, Viagra has also been shown to have alternative applications. For example, researchers have shown adding Viagra to cut flower water makes them last longer.

When they only gave the flowers one milligram of Viagra, they were found to stand erect for a week longer than the flowers that had been given plain water – a doubling of the length of time. flower conservation.

Counterfeit Viagra

Viagra is one of the most counterfeit drugs in the world. Due to its wide appeal, many patients attempt to purchase it without a prescription. Viagra can be purchased from online auction sites, online pharmacies, and even physical retail stores.

There are many risks involved in taking counterfeit Viagra. The fake tablets may not contain Viagra or too much Viagra. There have also been reports that counterfeit tablets contained blue printer ink – to give them that real Viagra look – illegal drugs like amphetamines and other unrelated drugs like the antibiotic metronidazole.

It is probably not genuine.
Julian Fong / Flickr, CC BY

The best way to make sure you’re not buying counterfeit Viagra is to have a trusted pharmacist fill out your in-store script. For those patients who need to fill out their Viagra script on the Internet, there are ways to check if the medication given to you is fake.

Look for the writing stamped on the shelves. Does it look crisp or does it look blurry? Also check their color consistency; you are looking to see if there are any areas that are darker or lighter blue than the rest of the tablet.

Then see if the tablets are smooth. Rough or pitted tablets are a sign of fake medicine.

Viagra is supplied in packs of four. If your strip contains more than four tablets, it is a counterfeit.

And, finally, Viagra is supplied only in the form of solid tablets. Your tablets are counterfeit if you have been provided with soft tablets, gel tablets or chewable tablets.

If you think you have received counterfeit tablets, take them to your local pharmacist for checking and disposal.

Cost

For the treatment of erectile dysfunction, Viagra is available in three doses (25, 50 and 100 milligrams) with four tablets per pack. The cost to the patient is the same regardless of the dose at $ 6.20 per sachet.

the australian Pharmaceutical benefit plan subsidizes the drug; the cost to the government is between $ 54 and $ 82 per pack depending on the brand. Patients can expect to pay more if they buy Viagra over the internet.

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