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Quick Facts About Erectile Dysfunction (aka ED)

  • Erectile dysfunction affects 100 million men worldwide.
  • The number of men affected by erectile dysfunction is expected to double by 2025.
  • Erectile dysfunction (ED) has a substantial impact on the pace of life and is a very general and untreated disease.
  • Erectile dysfunction is most common in men over 60, but it can occur in men of any age.
  • Erectile dysfunction (ED) also involves your spouse.
  • A tight dress does not induce erectile dysfunction. For decades, it has conquered a tale that wearing tight underwear, jeans, or other smug clothes could induce erectile dysfunction.
  • Some erectile dysfunction (ED) problems are psychological.
  • Erectile dysfunction (ED) can be a cautious sign of impending heart disease, early death, and increased blood pressure.

What is erectile dysfunction (aka ED)?

Erectile dysfunction (ED) means the continued inability to achieve and maintain an erection sufficient for satisfactory sexual performance. Erectile dysfunction has a substantial impact on the physical and psychological condition of men worldwide and can also impact the quality of life of sufferers and their members.

Penile erection is a complicated phenomenon that affects a delicate and coordinated harmony between the neurological, vascular and tissue boxes. This has arterial dilation, trabecular soft muscle relaxation, and activation of the human VENO occlusive tool.

The multiple common danger factors for erectile dysfunction are cardiovascular disease, hypertension, diabetes mellitus, hyperlipidemia, hypogonadism, lower urinary tract signs, and smoking.

Signs of erectile dysfunction may seem transient to most men, but in fact the symptomatology is continuous. It can generate a lot of negativity if not dined.

Sexual medicine experts report the reality that most cases facing erectile dysfunction (ED) do not recognize the extent of the condition and tend to forget about it.

Means of penis erection

Penile erection is a spinal reflex that is triggered by autonomic and bodily penile afferents and by supraspinal outcomes of visual, olfactory, and imaginary prompts. There are many central transmitters interested in erectile potency, some of them having a facilitating function and some having an inhibiting function.

The central transmitters having a facilitating function in penile erection are:

  • dopamine
  • peptides, such as oxytocin and adrenocorticotropin/α-Hormone stimulating melanocytes.
  • acetylcholine,
  • nitric oxide

The degree of compaction of soft muscle cells in the cavernous body is determined by the ratio of contracting and relaxing factors. Noradrenaline arranges both the smooth muscles of the corpora cavernosa and the penile vessels via the thrust of α1-adrenergic, while nitric oxide is considered the most important element for relaxation of penile vessels and cavernous bodies.

Nitric oxide is eliminated during sexual motivation. It starts the enzyme called guanylate cyclase, leading to an improvement in the status of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum. This, in turn, leads to relaxation of soft muscles, allowing increased blood flow to the penis. The cyclic guanosine monophosphate class is controlled by the rate of synthesis via guanylate cyclase and the rate of degradation via cyclic guanosine monophosphate hydrolyzing phosphodiesterase (aka PDE).

What are the many typical causes of erectile dysfunction (ED)?

Problems with blood circulation, nerve reserves or hormones can affect regular erectile function. Atherosclerosis is one of the conditions that cause problems with blood circulation. In patients with atherosclerosis, the arteries in the penis are restricted and blocked, preventing the blood flow needed to the penis to achieve an erection.

The most typical physical or organic reasons for erectile dysfunction are:

  • heart disease and narrowing of blood vessels
  • diabetes could be one of the common causes
  • increased blood pressure
  • high cholesterol
  • obesity and metabolic syndrome are also one of the main causes
  • Parkinson’s disease
  • multiple sclerosis
  • hormonal disorders, including thyroid conditions and testosterone deficiency
  • structural or anatomical disturbance of the penis, such as Peyronie’s disease
  • smoking, alcoholism, and abuse of the senses, such as cocaine use
  • therapies for prostate diseases
  • surgical difficulties
  • damage to the pelvic area or spinal cord
  • radiation therapy to the pelvic region.

Patients who are carrying medications and mourning erectile dysfunction should consult their health care skills to see if any of the medications may be causing the problem. These drugs also have illicit and/or recreational drugs. Medicines and drugs that cause erectile dysfunction or other sexual problems as side consequences are usually appointed for men without them understanding the dangers.

The drugs that could be interested in the case of erectile dysfunction are:

  • drugs that act on the main nervous system, including some sleeping pills and amphetamines
  • anti-stress treatments
  • certain cancer drugs, including chemotherapy drugs
  • drugs for prostate treatment
  • anticholinergics
  • hormonal pills
  • peptic ulcer medicine (cimetidine).
  • drugs to prevent high blood pressure
  • heart medications (digoxin)
  • antidepressants (monoamine oxidase inhibitors, especially serotonin reuptake inhibitors and tricyclic antidepressants)
  • opioid painkillers
  • few diuretics

Treatment of erectile dysfunction (ED)

Selective phosphodiesterase type 5 (aka PDE5I) inhibitors describe the first line of treatment for erectile dysfunction. These drugs are very effective, well tolerated and have very good safety forms. Four phosphodiesterase type 5 inhibitors are on the market: sildenafil, vardenafil, tadalafil and avanafil. These agents do not instantly cause penile erections but rather affect the reaction to sexual stimulation.

Sildenafil was the first in this series of phosphodiesterase type 5 inhibitors. In accordance with European policies, the choice between a short acting phosphodiesterase type 5 inhibitor and a long acting phosphodiesterase type 5 inhibitor is based on on the frequency of intercourse (less use or regular treatment, 2-4 times per week) and on the patient’s unique history.

Other erectile dysfunction drugs have:

Kamagra is also one of the best alternatives to Viagra because it is cheaper and it works the same way as Viagra and that is why people always tend to buy Kamagra.

Q1- What other therapies are available for erectile dysfunction? Can I dine my erectile dysfunction without drugs?

Lifestyle changes:

  • The following changes may benefit patients with erectile dysfunction (ED):
  • have a balanced diet;
  • maintain a healthy body weight;
  • fun in regular activities;
  • stop smoking;
  • avoiding too much alcohol and illicit drugs;
  • seek help for emotional and physiological problems.

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